Clindamycin: Uses, Dosage, Side‑Effects & Resistance
When tackling Clindamycin, a lincosamide antibiotic prescribed for skin, respiratory and bone infections. Also known as Cleocin, it blocks bacterial protein synthesis and is frequently chosen when patients can’t tolerate penicillins.
Clindamycin belongs to the broader class of antibiotics, drugs that kill or inhibit bacteria. This class includes familiar names like amoxicillin, azithromycin and cephalexin, all of which appear in our other guides. Understanding where clindamycin fits helps you compare its spectrum, side‑effect profile and cost against those alternatives.
One of the most common reasons doctors pick clindamycin is to treat skin infections, such as cellulitis, acne, and infected wounds. Its ability to reach high concentrations in skin tissue makes it a go‑to option for MRSA‑suspected cases. If you’ve ever wondered why some acne regimens include oral clindamycin, the answer lies in its anti‑inflammatory properties alongside the antibacterial action.
Dosage matters. Adult dosing typically ranges from 150 mg to 600 mg every six to eight hours, adjusted for infection severity and kidney function. For children, weight‑based dosing is standard, usually 8‑20 mg/kg per dose. Always check whether the drug formulation is oral, topical or injectable, because the route changes the required amount. Missed doses can lower drug levels and encourage drug resistance, a growing problem with overuse of broad‑spectrum agents.
Speaking of resistance, clindamycin resistance is tracked by the D‑test in labs. When bacteria show inducible resistance, the drug may look effective in a standard test but fail in practice. This is why clinicians pair clindamycin with susceptibility data whenever possible. Knowing the resistance patterns in your region can save you weeks of ineffective treatment.
Side‑effects are usually mild but worth noting. The most frequent complaint is gastrointestinal upset, especially diarrhea. A rarer but serious risk is Clostridioides difficile infection, which can cause severe colitis. Skin rashes, liver enzyme elevations, and taste disturbances also appear in patient reports. If any of these symptoms emerge, contact your provider promptly.
If you’re looking for clear guidance on Clindamycin, you’re in the right spot. Below you’ll find articles that compare clindamycin with other anti‑infectives, explain how to choose the right dosage, and outline safety tips for specific populations such as pregnant women and the elderly.
Our collection also covers practical topics like buying generic versions online, understanding insurance coverage, and managing side‑effects at home. Whether you’re a patient trying to understand your prescription or a healthcare professional refreshing your knowledge, the posts ahead offer concise, actionable information.
Ready to explore the details? Scroll down to dive into each guide and get the answers you need about clindamycin and related treatments.
Cleocin (Clindamycin) vs. Alternatives: Which Antibiotic Is Best?
Posted By Kieran Beauchamp On 12 Oct 2025 Comments (2)

A detailed comparison of Cleocin (clindamycin) with other acne and infection antibiotics, covering uses, side effects, cost, resistance and best‑fit scenarios.
READ MORE